6-Azidohexanoic Acid NHS Ester
作者:6-Azidohexanoic Acid NHS Ester 发布时间:2022-09-05 17:14:11
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分子量
254.24
分子式
C10H14N4O4
CAS
N/A
溶(解)度
DMSO, DMF, THF, DCM, Chloroform
纯度
>95% (HPLC)
外观
Slightly yellow oil
储存环境
-20°C. Desiccate
运输条件
Ambient temperatureAn azido-containing building block that can be used to derivatize primary amines with an azido group via a stable amide bond. The NHS ester reacts with primary amines at pH 7-9 forming a stable amide bond. The azide (N3) group reacts with terminal alkynes via CuAAC, strained cyclooctynes (e.g. DBCO or BCN compounds) via Cu-free click reaction or with phosphine-labeled molecules by a mechanism known as Staudinger chemistry, enabling efficient and specific conjugation of derivatized molecules in biological samples.