UV Cleavable Biotin-PEG2-Azide|CAS:1654739-36-2
作者:UV Cleavable Biotin-PEG2-Azide|CAS:1654739-36-2 发布时间:2022-09-01 11:56:55
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中文名:紫外线可裂解生物素-二聚乙二醇-叠氮化物英文名:UV Cleavable Biotin-PEG2-AzideCAS:1654739-36-2产品参数1
Catalog #:
Y-PE-3347
Name:
UV Cleavable Biotin-PEG2-Azide
CAS:
1654739-36-2
Formula:
C38H51N7O9S
MW:
781.9
Purity:
95%
Availability:
In Stock
Ships within:
24 hours
Storage condition:
-20℃
Shipping:
Ambient temperatureUV Cleavable Biotin-PEG2-Azide is a biotin linker. The azide group can react with either alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. Captured target can be released under mild photolysis conditions (365 nm) and results in a significant decrease of background signal due to non-specifically bound proteins.
UV Cleavable Biotin-PEG2-Azide is PEG derivative containing a biotin group and an azide group. The azide group can react to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. PEG Linkers may be useful in the development of antibody drug conjugates.